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The idea was so tempting. The drugs in the GLP-1 class, which include Wegovy and Ozempic, have shown themselves miraculous in the treatment of weight loss and other diseases. And some researchers hoped that the drugs could also help with some of the most difficult diseases to treat: those of the brain, such as Parkinson's ones.But now, at least for Parkinson's, that hope seems attenuated. A rigorous study that randomly assigned Parkinson's patients to take Exenatide, a relative of Ozimpic, has not shown absolutely any benefit or slowdown in the course of the degenerative disease after 96 weeks.And there has been no effect on the patient's symptoms, no effect on brain scans, no subgroup that showed any benefit. It doesn't matter how the researchers cut the data, the results were the same.Th...

Rev. Richard Williamson, a priest affiliated to a fleeing Catholic sect that caused a scandal in the church for his anti -Semitic declarations and the denial of the Holocaust, and which was excommunicated twice by the Vatican, died on Wednesday In Margate, England. He was 84 years old.His death, after suffering a cerebral hemorrhage, was confirmed by the schismatic Catholic sect of which he had been a longtime member, the Society of St. Pius X, in a press release issued by his headquarters in Switzerland.The company was founded in 1970 by the renegade traditionalist French archbishop, Marcel Lefebvre, who rejected the liberalizing dictates of the second Vatican Council of the mid -1960s, who, among other things, repudiated doctrinal anti -Semitism in the Church.Father Williamson was ordai...

There is a new living room game at Wall Street: guess Tiktok's next owner.President Trump signed an executive order in January which delayed the application of a law that prohibited the popular video app. Based on the order, the app must now be sold to a non -Chinese owner at the beginning of April.Since signed the order, Mr. Trump has dropped a burst of tips that are sometimes conflicting on how the next few weeks could take place: he suggested wanting a war of offers; He said the United States should have part of the app; He appointed Microsoft and Elon Musk as potential buyers, even if others have raised their hands.But the mechanics of a potential sale are still obscure.ByTedance, the owner of Tiktok, said for years that he cannot sell the app, in part because the Chinese government wo...

The new intelligence on the Iranian nuclear program convinced American officials that a secret team of the country's scientists is exploring a faster, even if more rough approach, to the development of an atomic weapon if Tehran's leadership decides to run for a bomb , according to the current and former American officials.The development also comes among the signs that the new president of Iran is actively looking for a negotiation with the Trump administration.The intelligence has been collected in the last months of the Biden administration, then transmitted to the national security team of President Trump during the transition of power, according to officials, who asked the anonymity to discuss sensitive details. The evaluation of intelligence warned that the engineers and scientists o...

The Us Food and Drug Administration has given the green light to two biotechnology companies for clinical studies that transplant genetically modified pig bodies in people with renal failure. In case of success, these studies could lead to the wider use of transparently transplantation, a dream of medical scientists for centuries.One of the companies, United Therapeutics Corporation, will begin its experimentation with six patients, but that number could possibly go up to 50. The other, Egenesis, said he would start with three patients and grow the study from there."We are entering a transformative era in organ transplantation," said Mike Curtis, president and CEO of Egenesi.Over the past three years, five patients are known to receive organs from pigs designed by these companies: two who ...

The decision of President Trump to impose large rates for some of the largest American commercial partners has sent shock waves through the markets all over the world on Monday.The dollar has strengthened, the oil prices increased and the main equity indices in the United States decreased at the beginning of the negotiations on Monday, although the S&P 500 and the heavy Nasdaq of technology subsequently regained some of their losses on the news that The rates of the goods from Mexico are ready to be delayed one month. The indices had come down 1 % by late morning. Markets in Asia and Europe also collapsed in Asia.When Mr. Trump was elected, many analysts and investors had swept away his most aggressive tariff speech as bluster intended to ask for negotiations from his global counterpartie...

A week ago, Openi has published a tool that can go online to shop or book a restaurants. Now it offers technology AI can collect information from the Internet and summarize them in concise reports.Open has revealed the new tool, called Deep Research, with a demonstration on YouTube on Sunday, days after showing technology to legislators, politicians and other Washington officials."It can carry out complex research tasks that may request a person from 30 minutes to 30 days," said Kevin Weil, Chief Product Officer in Openi, at the Washington event. On the contrary, deep research can carry out these tasks in 5-30 minutes, depending on the complexity.Artificial intelligence researchers call this type of technology an artificial intelligence agent. While chatbots can answer questions, write poe...

The new interim president of Syria, Ahmed al-Shara, arrived on Sunday in Saudi Arabia for his first foreign journey from his rebel coalition the longtime dictator Bashar al-Assad, saying that his country is looking for a true collaboration with The kingdom of the Gulf.Al-Shara landed at Riyad airport, in the Saudi capital on Sunday afternoon. The new flag of Syria flew next to the Saudi flag at the airport. Al-Shara later he met the hereditary prince of the reign rich in oil, Mohammed Bin Salman, according to the Syrian media and the Saudi state.The choice of Saudi Arabia for the first Al-Shara journey abroad was seen as a reflection of the married political alignments of Syria under the new leadership of the country: far from Iran, which was a key ally of the Assad regime and towards the ...

Javier presents himself as bewildered by the changes in his wife. He is in mourning, he says, the loss of the woman he married, starting with his physical self. “I liked to hear his body, his great body, next to me in bed, the softness. The extra belly and the extra booty were comforting and reassuring, "he says." I miss. The voluptuousness, being able to lean alongside her and hear it, for lack of a better word, drapping on me or me. Not It is more an option. "Before prescribing these drugs, the doctors responsible will advise patients to patients the known-diarrhea side effects, constipation, nausea, vomiting, headache-not the need for changes in the diet and physical exercise. They will explain the dosage program and may discuss costs. This, more or less, is where the professional guide...

The Ukrainian authorities said on Sunday that two air attacks a day before had killed at least 18 civilians, one of the highest tolls of one day so far this year and a dark reminder of the lasting devastation of the war while approaching his fourth year.The first strike occurred on Saturday morning when a Russian missile hit a residential building in the Ukrainian city of Poltava, almost 150 miles from the front line, killing at least 14 people, including two children, according to local emergency services. The videos of the consequences of the attack showed a section of the building reduced to rubble, with clothes and documents scattered in the area.A few hours later, the Ukrainian authorities said that a Russian bomb had crashed into a college to Southzha, a city in western Russia that i...